Free NEET Biology multiple-choice questions on Applications in Health. Attempt each question and reveal the answer with a full explanation.
Ultrasound of how much frequency is beamed into human body for sonography ? 15 - 30 MHZ 1 - 15 MHZ 45 - 70 MHZ 30 - 45 MHZ. The transgenic sheep 'Tracy', produced in Scotland, was engineered to produce high levels of which human protein in her milk? -1-antitrypsin -lactalbumin Insulin Factor IX Transgenic mice are being developed for use in: Testing the safety of vaccines before they are used on humans Producing large quantities of meat Studying the effect of gravity Producing expensive fur What percentage of all existing transgenic animals are mice, which are used primarily to study the effect of genes on body functions and diseases? Over 95% Exactly 50% Around 75% Less than 25% Ì' -1-antitrypsin is a biological product produced by transgenic animals and is used to treat: Emphysema Phenylketonuria (PKU) Cystic fibrosis Alzheimer's disease Transgenic animals are specifically designed to study the regulation of genes and how they affect the normal functions of the body and its development. This application is known as studying: Normal physiology and development Vaccine safety Chemical safety testing Biological products Which transgenic model animal is specifically used to study the treatment of the disease 'Cystic Fibrosis'? Transgenic mice Transgenic sheep Transgenic cow Transgenic pigs In Downstream Processing, the final product is formulated with suitable to ensure its stability and quality. Preservatives Antibiotics Restriction enzymes Divalent cations The milk of the transgenic cow 'Rosie' was considered nutritionally more balanced for human babies than natural cow milk because it contained: Human alpha-lactalbumin Human insulin Bovine growth hormone -galactosidase Which of the following is considered a 'biological product' obtained from transgenic animals for the treatment of human diseases? -1-antitrypsin Insulin Glucagon Thyroxine The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by Enzyme replacement therapy Periodic infusion of genetically engineered lymphocytes having functional ADA cDNA Administering adenosine deaminase activators Introducing bone marrow cells producing ADA into cells at early embryonic stages The first human hormone produced by recombinant DNA technology is :- Insulin Estrogen Thyroxin Progesterone Which of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes? phage Ti plasmid Retrovirus pBR 322 Now a days it is possible to detect the mutated gene causing cancer by allowing radioactive probe to hybridise its complementary DNA in a clone of cells, followed by its detection using autoradiography because : mutated gene completely and clearly appears on a photographic film mutated gene does not appear on a photographic film as the probe has no complementarity with it mutated gene does not appear on photographic film as the probe has complementarity with it mutated gene partially appears on a photographic film With regard to insulin choose correct options. (a) C-peptide is not present in mature insulin. (b) The insulin produced by rDNA technology has C-peptide. (c) The pro-insulin has C-peptide (d) A-peptide and B-peptide of insulin are interconnected by disulphide bridges. Choose the correct answer from the options given below (b) and (c) only (a), (c) and (d) only (a) and (d) only (b) and (d) only In gene therapy of Adenosine Deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because : Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages Lymphocytes from patient's blood are grown in culture, outside the body. Genetically engineered lymphocytes are not immortal cells. Retroviral vector is introduced into these lymphocytes. Statements related to human Insulin are given below. Which statement(s) is/are correct about genetically engineered Insulin? (a) Pro-hormone insulin contain extra stretch of C-peptide (b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them. (c) Insulin used for treating Diabetes was extracted from Cattles and Pigs. (d) Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone. (e) Some patients develop allergic reactions to the foreign insulin. Choose the most appropriate answer from the options given below: (b) only (c) and (d) only (c), (d) and (e) only (a), (b) and (d) only Match List I with List II : array ll List I & List II A. –I antitrypsin & I. Cotton bollworm B. Cry IAb & II. ADA deficiency C. Cry IAc & III. Emphysema D Enzyme replacement therapy & IV Corn borer array Choose the correct answer form the options given below: A-II, B-I, C-IV, D-III A-III, B-I, C-II, D-IV A-III, B-IV, C-I, D-II A-II, B-IV, C-I, D-III Which technique helps to identify a bacterial or viral pathogen in a human body even when its concentration is very low and clinical symptoms are not yet visible? Differential leucocyte count ELISA Total leucocyte count PCR In gene therapy to treat adenosine deaminase deficiency disorder, which of the patients blood cells are used ? Thrombocytes Erythrocytes Lymphocytes Both Erythrocytes and Lymphocytes When gene targetting involving gene amplification is attempted in an individual's tissue to treat disease, it is known as : Gene therapy Molecular diagnosis Safety testing Biopiracy Which one of the following techniques does not serve the purpose of early diagnosis of a disease for its early treatment? (1) Recombinant DNA Technology (2) Serum and Urine analysis (3) Polymerase Chain Reaction (PCR) technique (4) Enzyme Linked Immuno-Sorbent Assay (ELISA) technique Which of the following genetically engineered organisms was used by Eli Lilly to prepare human insulin? Phage Bacterium Yeast Virus The human protein named α-1-antitrypsin, obtained from transgenic animals, is used for the treatment of . Alzheimer’s disease Rheumatoid arthritis Emphysema Cystic fibrosis In transgenic animals developed for 'chemical safety testing', why are these animals sometimes preferred over normal animals? They are made more sensitive to the toxic substances They are completely resistant to all toxins They produce human proteins in their milk They have a longer lifespan than normal animals