Immunology — Practice Questions

Free NEET Biology multiple-choice questions on Immunology. Attempt each question and reveal the answer with a full explanation.

Damage to thymus in a child may lead to A reduction in haemoglobin content of blood A reduction in stem cell production Loss of antibody mediated immunity Loss of cell mediated immunity The cell-mediated immunity inside the human body is carried out by (1) T-lymphocytes (2) B-lymphocytes (3) Thrombocytes (4) Erythrocytes At which stage of HIV infection does one usually show symptoms of AIDS :- Within 15 days of sexual contact with an infected person. When the infected retro virus enters host cells. When HIV damages large number of helper T-Lymphocytes. When the viral DNA is produced by reverse transcriptase. Asthma may be attributed to : bacterial infection of the lungs allergic reaction of the mast cells in the lungs inflammation of the trachea accumulation of fluid in the lungs In higher vertebrates, the immune system can distinguish self-cells and non-self. If this property is lost due to genetic abnormality and it attacks self-cells, then it leads to :- Allergic response Graft rejection Auto-immune disease Active immunity Which of the following statements is correct ? AIDS is caused by a group of viruses called rhinovirus. Acquired immunity is pathogen specific. The exaggerated response of the immune system to certain antigens present in the environment is called Auto-immunity. Bone marrow acts as a filter of the blood by trapping blood borne micro-organisms. Which of the following is not an autoimmune disease? Alzheimer's disease Rheumatoid arthritis Psoriasis Vitiligo Colostrum the yellowish fluid, secreted by mother during the initial days of lactation is very essential to impart immunity to the new born infants because it contains (1) Immunoglobulin A (2) Natural killer cells (3) Monocytes (4) Macrophages Which of the following immune responses is responsible for rejection of kidney graft? Cell-mediated immune response Auto-immune response Humoral immune response Inflammatory immune response Identify the wrong statement with reference to immunity. When ready-made antibodies are directly given, it is called “Passive immunity”. Active immunity is quick and gives full response. Foetus receives some antibodies from mother, it is an example for passive immunity. When exposed to antigen (living or dead) antibodies are produced in the host’s body. It is called “Active immunity”. The Adenosine deaminase deficiency results into Parkinson's disease Digestive disorder Addison's disease Dysfunction of Immune system AIDS is caused by HIV that principally infects Activator B cells T4 lymphocytes Cytotoxic T cells All lymphocytes Given below are two statements: Statement I: Autoimmune disorder is a condition where body defense mechanism recognizes its own cells as foreign bodies. Statement II: Rheumatoid arthritis is a condition where body does not attack self cells. In the light of the above statements, choose the most appropriate answer from the options given below: Both Statement I and Statement II are incorrect Statement I is correct but Statement II is incorrect Statement I is incorrect but Statement II is correct Both Statement I and Statement II are correct Select the incorrect statement with respect to acquired immunity. Anamnestic response is elicited on subsequent encounters with the same pathogen. Anamnestic response is due to memory of first encounter. Acquired immunity is non-specific type of defense present at the time of birth. Primary response is produced when our body encounters a pathogen for the first time. In which blood corpuscles, the HIV undergoes replication and produces progeny viruses? T H cells B-lymphocytes Basophils Eosinophils Which of the following are Autoimmune disorders? A. Myasthenia gravis B. Rheumatoid arthritis C. Gout D. Muscular dystrophy E. Systemic Lupus Erythematosus (SLE) Choose the most appropriate answer from the options given below: A, B & D only A, B & E only B, C & E only C, D & E only Given below are two statements : Statement I : Bone marrow is the main lymphoid organ where all blood cells including lymphocytes are produced. Statement II : Both bone marrow and thymus provide micro environments for the development and maturation of T-lymphocytes. In the light of above statements, choose the most appropriate answer from the options given below : Both Statement I and Statement II are correct. Both Statement I and Statement II are incorrect. Statement I is correct but Statement II is incorrect. Statement I is incorrect but Statement II is correct. Identify the statement that is NOT correct. Constant region of heavy and light chains are located at C-terminus of antibody molecules Each antibody has two light and two heavy chains. The heavy and light chains are held together by disulfide bonds. Antigen binding site is located at C-terminal region of antibody molecules. Which of the following type of immunity is present at the time of birth and is a non-specific type of defence in the human body? Humoral Immunity Acquired Immunity Innate Immunity Cell-mediated Immunity After maturation, in primary lymphoid organs, the lymphocytes migrate for interaction with antigens to secondary lymphoid organ(s) / tissue(s) like A. thymus B. bone marrow C. spleen D. lymph nodes E. Peyer's patches Choose the correct answer from the options given below C, D, E only B, C, D only A, B, C only E, A, B only Which of the following conditions arises due to the presence of Rh-negative blood in the mother and Rh-positive blood in the foetus during the second pregnancy? Erythroblastosis foetalis Haemophilia Sickle cell anaemia Thalassemia An autoimmune disorder affecting neuromuscular junctions leading to fatigue, weakening and paralysis of skeletal muscle is: Myasthenia gravis Muscular dystrophy Tetany Arthritis Antibodies in our body are complex- (1) Lipoproteins (2) Steroids (3) Prostaglandins (4) Glycoproteins Which of the following is a genetic disorder characterized by progressive degeneration of skeletal muscle? Muscular dystrophy Myasthenia gravis Tetany Arthritis Which of the following is an example of an 'Autoimmune' disease related to the musculoskeletal system? Myasthenia gravis Muscular dystrophy Tetany Osteoporosis Which of the following Sexually Transmitted Infections (STIs) is caused by a protozoan? Trichomoniasis Gonorrhea Chlamydiasis Syphilis Which of the following is an example of a parthenocarpic fruit? Banana Apple Strawberry Cashew The principle of ELISA (Enzyme-Linked Immunosorbent Assay) is based on: Antigen-antibody interaction DNA-RNA hybridization Amplification of nucleic acids Sieving effect of agarose Antivenom injection contains preformed antibodies while polio drops that are administered into the body contain :- Activated pathogens Harvested antibodies Gamma globulin Attenuated pathogens Which of the following are secondary lymphoid organs? (a) Bone marrow (b) Tonsils (c) Spleen (d) Thymus Choose the correct answer from the options given below: (a) and (b) only (b) and (c) only (b) and (d) only (a) and (d) only Colostrum, secreted by mother during initial days of lactation, is abundant in . IgG IgM IgA IgD HIV that causes AIDS, first starts destroying (1) B-lymphocytes (2) Leucocytes (3) Thrombocytes (4) Helper T-lymphocytes If you suspect major deficiency of antibodies in a person to which of the following would you look for confirmatory evidence? serum globulins fibrinogen in the plasma haemocytes serum albumins Lysozyme that is present in perspiration, saliva and tears, destroys certain types of bacteria all viruses most virus-infected cells certain fungi A person likely to develop tetanus is immunized by administering : Weakned germs Dead germs Preformed antibodies Wide spectrum antibiotics Use of anti-histamines and steroids give a quick relief from - Headache Allergy Nausea Cough The letter T in T-lymphocyte refers to : Thymus Thyroid Thalamus Tonsil